Betadine Gargle and Mouthwash is rapidly virucidal, and fungicidal and is effective against all streptococcal organisms and may be used in the treatment of streptococcal tonsillitis and sore throat. Most sore throats are caused by viruses, Betadine kills most viruses responsible for sore throats. Betadine may be used in the treatment of oral thrush. Recommended in case of infected inflammatory conditions of the mouth and pharynx, including stomatitis, gingivitis, aphthous ulcers, pharyngitis, tonsillitis, and monilial infections.