Merck
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Description
Glucophage XR 1000mg is an oral antihyperglycemic agent containing Metformin Hydrochloride, indicated for the management of type 2 diabetes mellitus. It provides physiological support by decreasing hepatic glucose production and improving insulin sensitivity through enhanced peripheral glucose uptake.
Dosage & Administration
- Dosage: 1 tablet (1000mg) per administration.
- Frequency: Once daily.
- Method: Swallow the tablet whole; do not crush, chew, or bisect to preserve the extended-release matrix. Administer with 200ml of water.
- Timing: Administer with the evening meal to optimize gastrointestinal tolerance and maintain glycemic stability.
- Maximum Dose: Do not exceed 2000mg per day (2 tablets).
Safety & Storage
- Storage: Store in a dry location at temperatures below 30°C. Keep the container tightly closed.
- Warning: Monitor for symptoms of lactic acidosis. Temporarily discontinue use prior to radiologic studies involving iodinated contrast media.