Merck
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Description
Glucovance 500mg/2.5mg is a fixed-dose combination therapy utilizing Metformin Hydrochloride and Glibenclamide to manage type 2 diabetes mellitus. It provides physiological support by simultaneously addressing insulin resistance and insufficient pancreatic insulin secretion to achieve optimal glycemic targets.
Dosage & Administration
- Dosage: 1 tablet (500mg/2.5mg) per administration.
- Frequency: Once or twice daily.
- Method: Administer orally with 200ml of water. Swallow the tablet whole; do not crush, chew, or break.
- Timing: Administer with meals (breakfast and/or dinner) to optimize gastrointestinal tolerance and mitigate the risk of hypoglycemia.
Safety & Storage
- Storage: Store at controlled room temperature below 30°C. Keep in original packaging to protect from moisture.
- Warning: Monitor for signs of hypoglycemia (dizziness, sweating, tremors). Use with caution in elderly patients or those prone to lactic acidosis.