Most people are familiar with omega-3 fatty acids and their role in supporting heart and brain health. What fewer people know is that EPA and DHA do not work in isolation. When the body processes them, it produces a class of specialised molecules called Pro-Resolving Mediators, or PRMs, that act as the body's internal cleanup crew, helping to resolve inflammation, clear cellular debris, and restore balance after injury, illness, or intense exercise. Thorne's Pro-Resolving Mediators formula goes beyond standard omega-3 supplementation by delivering three pre-resolving mediators alongside EPA and DHA in a single gelcap: 18-HEPE derived from EPA, and 17-HDHA and 14-HDHA derived from DHA. This dual approach gives the body both the raw material and the activated precursors it needs to produce its own resolvins and protectins, the specific compounds that signal the body to bring inflammation back under control. The result is a more complete, targeted approach to inflammatory balance, recovery, and long-term tissue health. This is a formula designed for people who want to go beyond basic omega-3 supplementation and support the body's natural resolution pathways in a meaningful, science-backed way.

How to Use

Take 1 gelcap daily, or as recommended by your healthcare practitioner. Can be taken with or without food. Contains fish-derived ingredients. Consult a healthcare professional before use if pregnant.

Key Benefits

Delivers three pro-resolving mediator precursors alongside EPA and DHA in a single gelcap | Supports the body's natural ability to balance and resolve inflammatory responses | Promotes tissue repair and recovery after injury or exercise | Supports healthy brain structure and cognitive function | Promotes clearance of cellular debris following the inflammatory process | Supports cardiovascular, immune, and nerve health | Third-party tested and manufactured to Thorne's rigorous quality standards

Certifications: Gluten Free | Dairy Free | Soy Free | Made in USA