Thorne Vitamin B12 as Methylcobalamin delivers the most bioavailable form of B12 directly to your body - no conversion required. Unlike standard supplements that rely on cyanocobalamin (a synthetic form the liver must first process), Thorne's methylcobalamin is already in its biologically active, tissue-ready state, so your body can put it to work immediately across four essential functions: heart health, nerve health, blood cell formation, and healthy sleep.

Why Methylcobalamin Matters

• Methylcobalamin is the active, naturally occurring form of B12 that the body utilises directly - cyanocobalamin requires the liver to detoxify and convert it first

• Clinical evidence shows methylcobalamin accumulates significantly more in liver tissue and is retained longer than cyanocobalamin

• Urinary excretion of methylcobalamin is approximately one-third that of cyanocobalamin, indicating substantially greater tissue retention

• Essential for recycling homocysteine and forming internal methyl donors that support cardiovascular and neurological function

Key Benefits

• Heart Health: Supports healthy homocysteine levels to benefit cardiac function

• Nerve Function: Maintains optimal nerve signalling, supports myelin sheath integrity

• Blood Cell Formation: Supports healthy red blood cell production and oxygen transport

• Sleep Support: Helps maintain normal circadian rhythms and healthy methylation processes

• Energy Metabolism: Supports cellular energy production and reduces fatigue from B12 deficiency

• Brain and Cognitive Health: Supports mental clarity, focus, and mood stability

Key Ingredient

• Vitamin B12 (as Methylcobalamin) - 1mg (1000mcg) per capsule

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide. Free from: gluten, soy, dairy, eggs, tree nuts, peanuts, fish, shellfish.

Why Thorne

Thorne is the #1 recommended supplement brand by healthcare practitioners (2023 HCP Seller Survey) and the only supplement company to partner with Mayo Clinic on wellness research. Trusted by 100+ professional sports teams and partner to U.S. Olympic Teams. Every product undergoes four rounds of testing - raw ingredient, in-process, finished product, and stability testing.

Who Benefits Most

• Vegetarians and vegans (B12 is found almost exclusively in animal foods)

• Adults over 50 (absorption declines with age)

• Individuals with digestive conditions affecting absorption (e.g. gastritis, post-bariatric surgery)

• Those taking metformin or proton pump inhibitors (which deplete B12)

• Anyone experiencing fatigue, brain fog, tingling in extremities, or poor sleep

How to Use

1. Take 1 capsule one to three times daily, or as recommended by your healthcare practitioner.

2. Best taken in the morning or early afternoon with or without food.

3. Avoid taking late in the day as B12 may affect sleep if taken too close to bedtime.

4. Store tightly sealed in a cool, dry place.

Safety Information

This product is contraindicated in individuals with a history of hypersensitivity to any of its ingredients. Consult your healthcare practitioner before use if you are pregnant or breastfeeding. Keep out of reach of children. Use only if bottle seal is intact.